Combination of direct information methods and alignments improves contact prediction. Recently, several new contact prediction methods have been published. They use large sets of multiple aligned sequences and assume that correlations between columns in these alignments can be the results of indirect interaction. We demonstrate that combining predictions from two prediction methods, PSICOV. And two alignment methods, HHblits.

For better performance and speed. , and Elofsson, A.

Ultra rapid, accurate model quality assessment for protein structure prediction. It relies on stream computing algorithms for distance matrix comparison and is implemented in Python and OpenCL. It is designed to work on GPUs and has been tested on nVIDA GTX 460 and 560 platforms. PconsD has been benchmarked in CASP10.